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J Wood Selected Research

vatalanib (PTK787)

4/2005Soluble markers for the assessment of biological activity with PTK787/ZK 222584 (PTK/ZK), a vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitor in patients with advanced colorectal cancer from two phase I trials.
4/2004Angiogenesis inhibition by the novel VEGF receptor tyrosine kinase inhibitor, PTK787/ZK222584, causes significant anti-arthritic effects in models of rheumatoid arthritis.
12/2001Effect of VEGF receptor inhibitor PTK787/ZK222584 [correction of ZK222548] combined with ionizing radiation on endothelial cells and tumour growth.
10/2001Inhibition of growth and metastasis of human pancreatic cancer growing in nude mice by PTK 787/ZK222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases.
9/2000Effects of PTK787/ZK 222584, a specific inhibitor of vascular endothelial growth factor receptor tyrosine kinases, on primary tumor, metastasis, vessel density, and blood flow in a murine renal cell carcinoma model.
3/2000Treatment for malignant pleural effusion of human lung adenocarcinoma by inhibition of vascular endothelial growth factor receptor tyrosine kinase phosphorylation.
3/2000Inhibition of malignant ascites and growth of human ovarian carcinoma by oral administration of a potent inhibitor of the vascular endothelial growth factor receptor tyrosine kinases.

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J Wood Research Topics

Disease

14Neoplasms (Cancer)
07/2016 - 02/2000
6Schizophrenia (Dementia Praecox)
04/2011 - 01/2000
4Neoplasm Metastasis (Metastasis)
10/2001 - 03/2000
2Sarcoma (Soft Tissue Sarcoma)
01/2021 - 03/2015
2Human Influenza (Influenza)
06/2009 - 06/2001
2Iron Deficiencies
09/2008 - 07/2000
2Body Weight (Weight, Body)
05/2008 - 03/2000
2Psychotic Disorders (Schizoaffective Disorder)
04/2007 - 01/2000
2Colonic Neoplasms (Colon Cancer)
12/2001 - 03/2000
2Polyploidy
12/2000 - 02/2000
2Critical Illness (Critically Ill)
05/2000 - 01/2000
2Carcinoma (Carcinomatosis)
03/2000 - 03/2000
1COVID-19
01/2022
1Postoperative Nausea and Vomiting (PONV)
01/2020
1Pneumococcal Pneumonia
10/2018
1Necrosis
01/2017
1Anxiety Disorders (Anxiety Disorder)
02/2016
1Acquired Immunodeficiency Syndrome (AIDS)
10/2015
1Gliosis
10/2015
1Delirium
09/2015
1Bulimia (Binge Eating)
03/2015
1Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive)
03/2015
1Osteoradionecrosis
03/2015
1Type IV Ehlers-Danlos Syndrome
11/2014
1Dyspepsia (Indigestion)
12/2011
1Hypokalemia
11/2011
1Fatigue
11/2011
1Communicable Diseases (Infectious Diseases)
07/2011
1Cough
07/2011
1Respiratory Tract Infections (Respiratory Tract Infection)
07/2011
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
04/2011
1Bipolar Disorder (Manic Depressive Psychosis)
04/2011
1Wounds and Injuries (Trauma)
08/2010
1Seizures (Absence Seizure)
07/2010
1Gastritis
09/2008
1Bone Resorption
07/2008
1Stroke (Strokes)
10/2007
1Aphasia (Dysphasia)
10/2007
1Pain (Aches)
01/2007
1Urologic Neoplasms (Urological Cancer)
01/2007
1Prostatic Neoplasms (Prostate Cancer)
01/2007
1Colorectal Neoplasms (Colorectal Cancer)
04/2005
1Hyperalgesia
04/2004
1Inflammation (Inflammations)
04/2004
1Rheumatoid Arthritis
04/2004
1Experimental Arthritis
04/2004
1Arthritis (Polyarthritis)
04/2004

Drug/Important Bio-Agent (IBA)

7Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
04/2005 - 03/2000
7vatalanib (PTK787)IBA
04/2005 - 03/2000
7Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2001 - 03/2000
5Proteins (Proteins, Gene)FDA Link
04/2011 - 03/2000
4VaccinesIBA
01/2022 - 06/2001
4Phosphotransferases (Kinase)IBA
11/2001 - 03/2000
4Tyrosine (L-Tyrosine)FDA Link
11/2001 - 03/2000
3Tyrosine Kinase InhibitorsIBA
04/2005 - 10/2001
3Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
11/2001 - 03/2000
2Opioid Analgesics (Opioids)IBA
01/2020 - 09/2015
2Protein Isoforms (Isoforms)IBA
09/2011 - 08/2010
2IronIBA
09/2008 - 07/2000
2Messenger RNA (mRNA)IBA
05/2008 - 03/2000
2Biological ProductsIBA
04/2005 - 01/2000
2Angiogenesis InhibitorsIBA
04/2004 - 09/2000
2Imatinib Mesylate (Gleevec)FDA Link
11/2001 - 03/2000
1Antineoplastic Agents (Antineoplastics)IBA
01/2021
1Anesthetics (Anesthetic Agents)IBA
01/2020
1Viral AntigensIBA
01/2017
1Pharmaceutical PreparationsIBA
02/2016
1HIV Envelope Protein gp120IBA
10/2015
1Dinoprostone (PGE2)FDA Link
10/2015
1BenzodiazepinesIBA
09/2015
1Methamphetamine (Desoxyn)FDA LinkGeneric
03/2015
1Proton Pump InhibitorsIBA
12/2011
1Histone Deacetylase InhibitorsIBA
11/2011
1Histone Deacetylases (Histone Deacetylase)IBA
11/2011
1Troponin T (Troponin T1)IBA
11/2011
1Anti-Bacterial Agents (Antibiotics)IBA
07/2011
1HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA
04/2011
1Carrier Proteins (Binding Protein)IBA
04/2011
1trans- 1,4- Bis(2- chlorobenzaminomethyl)cyclohexane DihydrochlorideIBA
07/2010
1Sodium Oxybate (gamma Hydroxybutyrate)FDA Link
07/2010
1Eosine Yellowish-(YS) (Eosin)IBA
09/2008
1TabletsIBA
09/2008
15- (15- hydroxy(5- (3- pyridyl)(2- thienyl))methyl)- 1- methyl- 4- phenylpyrrolidin- 2- oneIBA
07/2008
1Coenzyme A Ligases (Acid-Thiol Ligases)IBA
04/2007
1DNA (Deoxyribonucleic Acid)IBA
04/2007
1GTP-Binding Proteins (G-Protein)IBA
02/2005
1CollagenIBA
04/2004
1CarrageenanIBA
04/2004
1AntigensIBA
04/2004
1Proteoglycans (Proteoglycan)IBA
04/2004

Therapy/Procedure

5Therapeutics
02/2016 - 09/2000
2Palliative Care (Palliative Therapy)
07/2016 - 01/2007
2Critical Care (Surgical Intensive Care)
05/2000 - 01/2000
1Anesthesia
01/2020
1Jaw Fixation Techniques
01/2020
1Oral Surgery (Maxillofacial Surgery)
01/2020
1Drug Therapy (Chemotherapy)
03/2015
1Radiotherapy
03/2015
1Coronary Artery Bypass (Coronary Artery Bypass Surgery)
11/2014
1Language Therapy (Language Training)
10/2007